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Systematic Reviews: Meta-analysis

A Synthesis and Evaluation of existing evidence

Meta-Analysis

Meta-Analyses: Meta-analyses are statistical techniques used to combine the results of multiple studies quantitatively to produce a summary effect estimate. They involve pooling data from individual studies to calculate an overall effect size and assess the consistency and magnitude of the effect across studies. Meta-analyses are often conducted as part of systematic reviews but can also be standalone analyses.

  • Methodology: Meta-analyses use statistical techniques to combine the results of multiple studies quantitatively to produce a summary effect estimate. They involve pooling data from individual studies, calculating overall effect sizes and confidence intervals, and assessing heterogeneity across studies. Meta-analyses may be conducted as part of systematic reviews or as standalone analyses.
  • Objectives: The primary objective of meta-analyses is to provide a quantitative synthesis of the results of individual studies to estimate the overall effect size and assess the consistency and magnitude of the effect across studies. Meta-analyses aim to enhance statistical power, improve precision of effect estimates, and provide more robust evidence for decision-making.
  • Applications: Meta-analyses are used in various fields to synthesize quantitative evidence from multiple studies on a particular topic or intervention. They are often used to assess the effectiveness of healthcare interventions, evaluate the safety of treatments, explore the association between risk factors and outcomes, and identify sources of heterogeneity in study results.